Conan O'Brien had his hands full Wednesday night with William Shatner.
The former Captain Kirk -- slouching, sweating and watery-eyed -- mumbled throughout his interview, before O'Brien teased Shatner for not flashing a Star Trek Vulcan hand signal correctly. Shatner struggled, eventually opting to flash Conan the middle finger, which NBC blurred out with pixels.
A frazzled O'Brien then stole back the spotlight, jumping on his table and asking Shatner, "What is wrong with you?!?"