Oprah Winfrey is talking about the only time in her life she has suffered from depression - revealing the episode sent her into "a massive mac and cheese eating tailspin."

The talk show titan opens up to CNN's Piers Morgan, and RadarOnline.com can bring you a clip from the revealing interview.

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The 56-year-old billionaire shares that she believes her biggest failure to date was the 1998 movie adaptation of Toni Morrison's Beloved, which she produced and starred in.

Oprah says it was a project that: "I had, and still have such a passion for."