Nobody messes with Nancy Grace -- and RadarOnline.com has the video to prove it!

The spitfire television host is not going to let Joran Van Der Sloot’s friends defend him and blame his latest victim, Stephany Flores, for her own death.

In an exclusive interview Nancy rails on John Ludwick, a friend of Joran’s who claims that he killed Flores because he was suffering from post traumatic stress -- and that it was her fault for being there.