Melissa McCarthy knocked it out of the park as host of Saturday Night Live October 1.

The Emmy-winning star of Mike & Molly was fearless as she sang and danced, did pratfalls and crawled up stairs, wore crazy costumes and drank salad dressing -- all in the name of making them laugh.

One of her wackiest bits was as 1930s film star Lulu Diamonds.  You can watch it here on RadarOnline.com. Be prepared to LOL.

John Mayer and a team of celebrities have teamed-up to do a hilarious charity video to fight malaria – urging people to donate money so that Third World kids can reach the same age as teen sensation Justin Bieber!

In the wacky commercial, which you can watch here on RadarOnline.com, Mayer is joined by B.J. Novak, Jeff Probst and Rachel Harris as the celebrities urge people to buy $10 mosquito nets to help prevent one million contracting the deadly disease.

VIDEO: Justin Bieber, Bow Wow Come Out For A Good Cause

“Almost a million people die every year from malaria,” Mayer says at the beginning of the video. He continues: “And of that number 85% die under the age of Justin Bieber.”